Gene
fbxw4
- ID
- ZDB-GENE-000516-1
- Name
- F-box and WD repeat domain containing 4
- Symbol
- fbxw4 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to be involved in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process. Predicted to localize to SCF ubiquitin ligase complex. Human ortholog(s) of this gene implicated in split hand-foot malformation 3. Orthologous to human FBXW4 (F-box and WD repeat domain containing 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR001810 | F-box domain |
| Family | IPR052301 | SCF Complex F-box/Wd Repeat-Containing Protein |
| Homologous_superfamily | IPR015943 | WD40/YVTN repeat-like-containing domain superfamily |
| Homologous_superfamily | IPR036047 | F-box-like domain superfamily |
| Homologous_superfamily | IPR036322 | WD40-repeat-containing domain superfamily |
| Repeat | IPR001680 | WD40 repeat |
Domain Details Per Protein
| Protein | Length | F-box domain | F-box-like domain superfamily | SCF Complex F-box/Wd Repeat-Containing Protein | WD40 repeat | WD40-repeat-containing domain superfamily | WD40/YVTN repeat-like-containing domain superfamily |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q9IBH3
|
392 |
Interactions and Pathways
No data available
Plasmids
No data available