Gene

celf1

ID
ZDB-GENE-000501-1
Name
cugbp, Elav-like family member 1
Symbol
celf1 Nomenclature History
Previous Names
  • brul (1)
  • Bruno-like (1)
  • cb920 (1)
  • cugbp1
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Enables mRNA 3'-UTR binding activity. Involved in several processes, including developmental cell growth; liver development; and pancreas morphogenesis. Acts upstream of or within several processes, including embryonic liver development; endodermal digestive tract morphogenesis; and positive regulation of mRNA catabolic process. Located in pole plasm. Is expressed in several structures, including eye; gonad; lens placode; pectoral fin; and solid lens vesicle. Orthologous to human CELF1 (CUGBP Elav-like family member 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
13 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With celf1 Human Ortholog
No data available
Associated With celf1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR034196 CELF1/2, RNA recognition motif 1
Domain IPR034198 CELF1/2, RNA recognition motif 2
Domain IPR034199 CELF1/2, RNA recognition motif 3
Family IPR002343 Paraneoplastic encephalomyelitis antigen
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Domain Details Per Protein
Protein Length CELF1/2, RNA recognition motif 1 CELF1/2, RNA recognition motif 2 CELF1/2, RNA recognition motif 3 Nucleotide-binding alpha-beta plait domain superfamily Paraneoplastic encephalomyelitis antigen RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:E9QEH4 228
UniProtKB:Q9IBD0 501
UniProtKB:E9QIE8 169
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-cugbp1 polyclonal Rabbit
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations