Gene

bdnf

ID
ZDB-GENE-000412-1
Name
brain-derived neurotrophic factor
Symbol
bdnf Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have growth factor activity and nerve growth factor receptor binding activity. Involved in multicellular organismal response to stress and nervous system development. Predicted to localize to several cellular components, including axon; dendrite; and synaptic vesicle. Is expressed in several structures, including blastoderm; digestive system; nervous system; oral region; and pericardial region. Human ortholog(s) of this gene implicated in several diseases, including cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); obstructive sleep apnea; and status epilepticus. Orthologous to human BDNF (brain derived neurotrophic factor).
Genome Resources
Note
None
Expression
All Expression Data
59 figures from 24 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bdnf Human Ortholog
No data available
Associated With bdnf Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019846 Nerve growth factor conserved site
Domain IPR002072 Nerve growth factor-related
Family IPR020408 Nerve growth factor-like
Family IPR020430 Brain-derived neurotrophic factor
Homologous_superfamily IPR029034 Cystine-knot cytokine
Domain Details Per Protein
Protein Length Brain-derived neurotrophic factor Cystine-knot cytokine Nerve growth factor conserved site Nerve growth factor-like Nerve growth factor-related
UniProtKB:E9QIT5 184
UniProtKB:C5IG38 232
UniProtKB:B0V301 239
UniProtKB:Q6NZ01 270
UniProtKB:F1Q5K0 143
UniProtKB:Q9YH42 270
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-bdnf polyclonal Rabbit
  • IHC
  • WB
Millipore
7
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations