Gene
bdnf
- ID
- ZDB-GENE-000412-1
- Name
- brain-derived neurotrophic factor
- Symbol
- bdnf Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 7 Mapping Details/Browsers
- Description
- Predicted to have growth factor activity and nerve growth factor receptor binding activity. Involved in multicellular organismal response to stress and nervous system development. Predicted to localize to several cellular components, including axon; dendrite; and synaptic vesicle. Is expressed in several structures, including blastoderm; digestive system; nervous system; oral region; and pericardial region. Human ortholog(s) of this gene implicated in several diseases, including cognitive disorder (multiple); congenital central hypoventilation syndrome; neurodegenerative disease (multiple); obstructive sleep apnea; and status epilepticus. Orthologous to human BDNF (brain derived neurotrophic factor).
- Genome Resources
- Note
- None
- All Expression Data
- 59 figures from 24 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
- MGC:76834 (7 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Brain-derived neurotrophic factor | Cystine-knot cytokine | Nerve growth factor conserved site | Nerve growth factor-like | Nerve growth factor-related |
---|---|---|---|---|---|---|
UniProtKB:E9QIT5
|
184 | |||||
UniProtKB:C5IG38
|
232 | |||||
UniProtKB:B0V301
|
239 | |||||
UniProtKB:Q6NZ01
|
270 | |||||
UniProtKB:F1Q5K0
|
143 | |||||
UniProtKB:Q9YH42
|
270 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl