ZFIN is now using GRCz12tu for Genomic Data
Gene
dazl
- ID
- ZDB-GENE-000405-6
- Name
- deleted in azoospermia-like
- Symbol
- dazl Nomenclature History
- Previous Names
-
- zDAZL
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables mRNA 3'-UTR binding activity; sequence-specific DNA binding activity; and translation activator activity. Acts upstream of or within 3'-UTR-mediated mRNA stabilization; germ-line cyst formation; and negative regulation of miRNA-mediated gene silencing. Located in cytoplasm. Is expressed in several structures, including blastodisc; germ line cell; gonad; unfertilized egg; and yolk. Orthologous to several human genes including DAZL (deleted in azoospermia like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 42 figures from 32 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 6 figures from Bertho et al., 2021
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000504 | RNA recognition motif domain |
| Domain | IPR037551 | DAZ, RNA recognition motif, vertebrates |
| Domain | IPR043628 | DAZ domain |
| Homologous_superfamily | IPR012677 | Nucleotide-binding alpha-beta plait domain superfamily |
| Homologous_superfamily | IPR035979 | RNA-binding domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | DAZ domain | DAZ, RNA recognition motif, vertebrates | Nucleotide-binding alpha-beta plait domain superfamily | RNA-binding domain superfamily | RNA recognition motif domain |
|---|---|---|---|---|---|---|---|
| UniProtKB:Q9YGW7 | InterPro | 229 | |||||
| UniProtKB:Q1LUN6 | InterPro | 229 | |||||
| UniProtKB:A0A8M2BHE4 | InterPro | 212 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
- Genome Browsers