Gene

actb2

ID
ZDB-GENE-000329-3
Name
actin, beta 2
Symbol
actb2 Nomenclature History
Previous Names
  • bact2
  • bactin2 (1)
  • fa56g06
  • fb38a10
  • wu:fa56g06 (1)
  • wu:fb38a10 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to be a structural constituent of postsynaptic actin cytoskeleton. Predicted to localize to several cellular components, including actin filament; dense body; and focal adhesion. Is expressed in several structures, including blastomere; brain; eye; musculature system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Baraitser-Winter syndrome and autosomal dominant nonsyndromic deafness 20. Orthologous to several human genes including ACTB (actin beta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 16 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With actb2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Baraitser-Winter syndrome Alliance Baraitser-Winter syndrome 1 243310
?Dystonia, juvenile-onset 607371
Associated With actb2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR004001 Actin, conserved site
Conserved_site IPR020902 Actin/actin-like conserved site
Family IPR004000 Actin family
Homologous_superfamily IPR043129 ATPase, nucleotide binding domain
Domain Details Per Protein
Protein Length Actin/actin-like conserved site Actin, conserved site Actin family ATPase, nucleotide binding domain
UniProtKB:A0FKD7 30
UniProtKB:B2GTB1 375
UniProtKB:F1QC15 128
UniProtKB:A8WG05 375
UniProtKB:Q7ZVF9 375
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations