Gene

fzd8a

ID
ZDB-GENE-000328-3
Name
frizzled class receptor 8a
Symbol
fzd8a Nomenclature History
Previous Names
  • fz5
  • fz8a
  • fzc
  • wu:fd02c05
  • zfzc
  • zg05
Type
protein_coding_gene
Location
Chr: 24 Mapping Details/Browsers
Description
Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity. Involved in canonical Wnt signaling pathway; eye field cell fate commitment involved in camera-type eye formation; and neurogenesis. Predicted to localize to integral component of membrane and plasma membrane. Is expressed in several structures, including digestive system; mesoderm; nervous system; neural keel; and pectoral fin. Orthologous to human FZD8 (frizzled class receptor 8).
Genome Resources
Note
None
Expression
All Expression Data
21 figures from 10 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
12 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fzd8a Human Ortholog
No data available
Associated With fzd8a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000539 Frizzled/Smoothened, transmembrane domain
Domain IPR017981 GPCR, family 2-like
Domain IPR020067 Frizzled domain
Domain IPR041776 Frizzled 8, cysteine-rich domain
Family IPR015526 Frizzled/secreted frizzled-related protein
Homologous_superfamily IPR036790 Frizzled cysteine-rich domain superfamily
Domain Details Per Protein
Protein Length Frizzled 8, cysteine-rich domain Frizzled cysteine-rich domain superfamily Frizzled domain Frizzled/secreted frizzled-related protein Frizzled/Smoothened, transmembrane domain GPCR, family 2-like
UniProtKB:Q9W6E4 579
UniProtKB:Q9PTT7 579
UniProtKB:Q90446 192
UniProtKB:Q9YI00 579
Transcripts
Genome Browsers
Interactions and Pathways
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations