Gene
zic1
- ID
- ZDB-GENE-000208-4
- Name
- zic family member 1 (odd-paired homolog, Drosophila)
- Symbol
- zic1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II transcription regulatory region sequence-specific DNA binding activity; and zinc ion binding activity. Involved in brain development and embryonic retina morphogenesis in camera-type eye. Predicted to localize to nucleus. Is expressed in several structures, including central nervous system; neural keel; neural plate; neural rod; and presumptive neural plate. Human ortholog(s) of this gene implicated in Dandy-Walker syndrome and craniosynostosis. Orthologous to human ZIC1 (Zic family member 1).
- Genome Resources
- Note
- None
- All Expression Data
- 70 figures from 43 publications
- Cross-Species Comparison
- High Throughput Data
-
- GEO (1) Expression Atlas (1)
Wild Type Expression Summary
- All Phenotype Data
- 7 figures from Maurus et al., 2009
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ZIC protein, zinc finger domain | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|
|
UniProtKB:A4KUG6
|
285 | |||
|
UniProtKB:O93311
|
442 | |||
|
UniProtKB:Q9PVD6
|
183 |
Interactions and Pathways
No data available
Plasmids
No data available