Gene

ppardb

ID
ZDB-GENE-000112-47
Name
peroxisome proliferator-activated receptor delta b
Symbol
ppardb Nomenclature History
Previous Names
  • FAAR (1)
  • PPAR[b](II)
  • pparb2
  • fc59g04
  • fk47c06
  • NR1C2-B (1)
  • nr1c2b (1)
  • NUC1 (1)
  • wu:fc59g04
  • wu:fk47c06
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II repressing transcription factor binding activity. Predicted to be involved in several processes, including negative regulation of cholesterol storage; positive regulation of fatty acid metabolic process; and regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in brain; intestine; liver; and ovary. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human PPARD (peroxisome proliferator activated receptor delta).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
13 figures from 7 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppardb Human Ortholog
No data available
Associated With ppardb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000536 Nuclear hormone receptor, ligand-binding domain
Domain IPR001628 Zinc finger, nuclear hormone receptor-type
Family IPR001723 Nuclear hormone receptor
Family IPR003074 Peroxisome proliferator-activated receptor
Homologous_superfamily IPR013088 Zinc finger, NHR/GATA-type
Homologous_superfamily IPR035500 Nuclear hormone receptor-like domain superfamily
Domain Details Per Protein
Protein Length Nuclear hormone receptor Nuclear hormone receptor, ligand-binding domain Nuclear hormone receptor-like domain superfamily Peroxisome proliferator-activated receptor Zinc finger, NHR/GATA-type Zinc finger, nuclear hormone receptor-type
UniProtKB:Q90Z66 368
UniProtKB:A9C4A3 120
UniProtKB:O42545 31
UniProtKB:A9C4A4 219
UniProtKB:A9C4A5 517
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations