ZFIN Fish: WT + MO2-nr4a2a,nr4a2b

ZFIN ID: ZDB-FISH-150901-20975

ZFIN ID: ZDB-FISH-150901-20975

HUMAN DISEASE MODELED by WT + MO2-nr4a2a,nr4a2b
No data available

GENE EXPRESSION
Gene expression in WT + MO2-nr4a2a,nr4a2b

RNA expression

Expressed Gene	Structure	Conditions	Figures
nr4a1	midbrain hindbrain boundary pretectum ventral telencephalon	standard conditions	Fig. SD8 from Blin et al., 2008
nr4a2a	whole organism	standard conditions	Fig. S3 from Luo et al., 2008
nr4a2b	(not) caudal tuberculum dorsal thalamus floor plate rhombomere 1 forebrain (not) preoptic area pretectum telencephalon (not) ventral thalamus whole organism	standard conditions	Fig. SD8 from Blin et al., 2008 Fig. 5 , Fig. S3 from Luo et al., 2008
nr4a3	habenula medulla oblongata pretectum rhombomere 1 ventral telencephalon ventral thalamus	standard conditions	Fig. SD8 from Blin et al., 2008
slc6a3	caudal tuberculum	standard conditions	Fig. 4 from Luo et al., 2008
th	caudal tuberculum diencephalon forebrain hypothalamus locus coeruleus olfactory bulb periventricular nucleus of caudal tuberculum dopaminergic neuron preoptic area pretectum ventral thalamus dopaminergic neuron	standard conditions	Fig. 8 from Chen et al., 2012 Fig. 4 , Fig. SD10 from Blin et al., 2008 Fig. 4 , Fig. 5 from Luo et al., 2008

Protein expression No data available

Reporter gene expression No data available

PHENOTYPE
Phenotype in WT + MO2-nr4a2a,nr4a2b

Phenotype	Conditions	Figures
brain neuron apoptotic, abnormal	standard conditions	Fig. 7 from Blin et al., 2008
caudal tuberculum adrenergic neuron decreased amount, abnormal	standard conditions	Fig. 4 from Luo et al., 2008
forebrain adrenergic neuron decreased amount, abnormal	standard conditions	Fig. 5 from Luo et al., 2008
forebrain neuron development disrupted, abnormal	standard conditions	Fig. 4 , Fig. 5 from Luo et al., 2008
locomotion involved in locomotory behavior increased occurrence, abnormal	standard conditions	Fig. 8 from Blin et al., 2008
olfactory bulb adrenergic neuron decreased amount, abnormal	standard conditions	Fig. 4 from Luo et al., 2008
periventricular nucleus of caudal tuberculum has fewer parts of type dopaminergic neuron, abnormal	standard conditions	Fig. 8 from Chen et al., 2012
preoptic area adrenergic neuron decreased amount, abnormal	standard conditions	Fig. 4 from Luo et al., 2008
pretectum adrenergic neuron decreased amount, abnormal	standard conditions	Fig. 4 from Luo et al., 2008
ventral thalamus has fewer parts of type dopaminergic neuron, abnormal	standard conditions	Fig. 8 from Chen et al., 2012
whole organism increased behavioural activity, abnormal	standard conditions	Fig. 8 from Blin et al., 2008

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