FIGURE

FIGURE 3

ID

ZDB-FIG-260512-12

Publication

Nieoczym et al., 2026 - Studies on the anticonvulsant potential of 6-gingerol, an active ingredient of ginger rhizome

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FIGURE 3

The effect of 6-gingerol on hypolocomotion in the PILO-induced seizure model in larval zebrafish. After 22 h long incubation in different 6-gingerol concentrations (12.5–37.5 μM) larvae were exposed to PILO (50 mM) and after 2 min delay analysis of locomotor activity started. Results of the experiments are shown as distance traveled in 2 min-long time bins (A). Time-bin analyses are presented descriptively; statistical inference marked was based on total distance traveled within 28 min (B). Data were analyzed using Kruskal–Wallis test with Dunn’s multiple comparison test: KW = 25.34, p < 0.001. Data are shown as median + 95% confidence limits (n = 32–48 per group). *p < 0.05. 6-GIN, 6-gingerol; miliQW, miliQ water; PILO, pilocarpine hydrochloride; Veh, vehicle.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Conditions:	chemical treatment by environment: pilocarpine chemical treatment by environment: pilocarpine
Observed In:	swimming behavior
Stage:	Day 4

Phenotype Detail

Acknowledgments

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