FIGURE

Fig. 5

ID

ZDB-FIG-260413-73

Publication

Shang et al., 2026 - Endoplasmic reticulum targeted photosensitizer with high photostability and dual ROS generation for breast cancer PDT via apoptosis and pyroptosis

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Fig. 5

(A) ROS generation capability in 4T1 cells under different treatment conditions (n = 3). (B) Cell morphology changes in 4T1 cells under different treatment conditions. (C) Mitochondrial membrane potential in 4T1 cells under different treatment conditions (n = 3). (D) live/dead cell staining and CCK-8 (n = 6) of 4T1 cells after various treatments. Scale bar = 20 μm. (E) Apoptosis of 4T1 cells after flow cytometry analyzed different treatments (n = 3). Quadrants were defined as follows: Q1 (Annexin V⁻/PI⁺, necrotic cells), Q2 (Annexin V⁺/PI⁺, late apoptotic/necrotic cells), Q3 (Annexin V⁺/PI⁻, early apoptotic cells), and Q4 (Annexin V⁻/PI⁻, viable cells). A minimum of 1 × 10⁴ single-cell events were acquired per sample for quantitative analysis.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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