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Social preference is improved in ube3a mutants following change of the environmental context. a Scheme illustrating the experimental setup for social preference using conspecifics; created with BioRender. b Cumulative time spent in the ROI (shoal or empty) for WT and mutants (N = 10 for WT, N = 13 for mutant; Wilcoxon matched-pairs signed rank test). c Social preference-related parameters measured for the WT and mutants (N = 10 for WT, N = 13 for mutant; unpaired t test). d Scheme illustrating the experimental setup for non-social preference using glass marbles; created with BioRender. e Cumulative time spent in ROI (object or empty) for the WT and mutants (N = 11 for WT, N = 10 for mutant; Wilcoxon matched-pairs signed rank test). f Nonsocial preference-related parameters measured for WT and mutants (N = 11 for WT, N = 10 for mutant; unpaired t test). The data are presented as the mean ± SEM. ns: non-significant, **P < 0.01.
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