FIGURE

Figure S3.

ID

ZDB-FIG-260105-52

Publication

Li et al., 2026 - Stage- and tissue-specific gene editing using 4-OHT-inducible Cas9 in whole organism

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Figure S3.

Off-target analysis of the tbxta locus with WGS and NGS. (A) Schematic showing PGC collection for WGS. (B) Bar chart showing the mutation rates of PGCs within 4-OHT– or DMSO-treated embryos at the tbxta locus. Red letters indicate the sequence of tbxta target sites. Target site, tbxta gRNA target site; R1 to R4, the predicted tbxta gRNA off-target sites. INDEL, insertion-deletion; REF, reference genome; SNV, single-nucleotide variant.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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