FIGURE

Fig. 5

ID

ZDB-FIG-251113-106

Publication

An et al., 2025 - -A novel peptide SMIM45-107aa promotes HCC progression via MTDH pathways and its anticancer peptide derivative

Other Figures

All Figure Page

Back to All Figure Page

Fig. 5

SMIM45-107aa activated the AKT signaling pathway by modulating MGST1 and MTDH. (A) Proteomics analysis was employed to identify differentially expressed genes in SK-Hep1 cells between SMIM45-107aa-ovexression or knockdown groups and the control group (log₂ fold < 1.2, p < 0.5). (B) Venn diagram showing the overlap of differentially expressed proteins identified in SMIM45-107aa-overexpression and SMIM45-107aa-knockdown groups. (C) The GO analysis of the 42 differentially expressed genes. (D) The pathway enrichment analysis of the 42 differentially expressed genes. (E–F) Western blot analysis of indicated proteins in SMIM45-107aa-overexpression SK-Hep1 and SNU449 cells

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ J Transl Med