FIGURE

Fig. 5.

ID

ZDB-FIG-250828-173

Publication

Petzold et al., 2025 - Connexin 41.8 governs timely haematopoietic stem and progenitor cell specification

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Fig. 5.

Proposed model of the role of Cx41.8 in HSPC specification. Cx41.8 localises to the mitochondria in haemogenic endothelial cells, allowing mitochondrial ROS production which stabilises Hif1/2α, which in turn induces gata2b expression via Notch1a/b signalling. Created in BioRender by Petzold, T., 2025. https://BioRender.com/konhezh. This figure was sublicensed under CC-BY 4.0 terms.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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