FIGURE

Figure 6.

ID

ZDB-FIG-250801-93

Publication

Mo et al., 2025 - Biocompatible exosomes derived from Pinctada martensii mucus for therapeutic melanin regulation via α-MSH/NF-κB/MITF pathway

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Figure 6.

The effect of PMMEXOs on excessive pigmentation of the ear skin in C57BL/6 mice induced by UVB irradiation. (A) Time graph of the mouse experimental procedure. (B) Representative images of pigmentation on the skin of mouse ears. The circles indicate the areas irradiated by UVB. (C) Representative images of HE staining of mouse ear skin tissue. Scale bars =200 μm. (D) Statistical analysis of the corresponding epidermal thickness of the ear skin. (E) Representative images of Fontana–Masson staining of mouse ear skin tissue. The melanin pigment indicated by the arrow. Scale bars =200 μm. (F) Statistical analysis of the corresponding melanin content. n = 3, data are expressed as mean ± SD, one-way analysis of variance was used for statistical significance. **P < 0. 01, ****P < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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