FIGURE

Fig. 5

ID

ZDB-FIG-250509-10

Publication

Yang et al., 2025 - Total flavonoids of litchi seed inhibit breast cancer metastasis by regulating the PI3K/AKT/mTOR and MAPKs signaling pathways

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Fig. 5

Network pharmacology prediction results. (A) Compound-target network. Green nodes (left) represent 36 flavonoid compounds from litchi seeds, while yellow nodes (right) correspond to the 559 targets associated with these compounds. (B) Venn diagram showing 325 overlapping genes between the 559 potential therapeutic targets of TFLS and 3687 breast cancer-related genes. (C) Compound-disease-shared targets network. Red nodes represent TFLS, green nodes represent breast cancer, and blue square nodes indicate the 325 overlapping genes. (D) PPI network of the common targets. The diagram illustrates interactions among the 325 overlapping targets. Node sizes range from large to small based on degree of freedom, with the 36 key targets located in the inner two circles. (E) Top 20 KEGG pathways enriched from the 36 key targets.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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