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Fig. 3

ID

ZDB-FIG-250318-3

Publication

Vaz-Rodrigues et al., 2025 - Tick salivary proteins metalloprotease and allergen-like p23 are associated with response to glycan α-Gal and mycobacterium infection

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Fig. 3

Characterization of IgM antibody titers in zebrafish AGS model treated with tick salivary proteins. Experiment 1. Zebrafish were treated with recombinant tick salivary proteins, metalloprotease (MET) or allergen-like p23 (p23), in combination with saliva non-protein fraction (NPF) and, in comparison with tick saliva, saliva NPF, Subolesin (SUB)-NPF and PBS. (A) IgM antibody titers against tick salivary gland (SG) protein extract. (B) IgM antibody titers against α-Gal. (C) IgM antibody titers against SUB. (D) IgM antibody titers against tick protein p23. (E) IgM antibody titers against tick protein MET. Experiment 2. Zebrafish were treated with a combination (Mix) that included both recombinant tick salivary proteins, MET and p23, with NPF and in comparison, with tick saliva, and PBS. (F) IgM antibody titers against tick SG protein extract. (G) IgM antibody titers against α-Gal. (H) IgM antibody titers against tick protein p23. (I) IgM antibody titers against tick protein MET. Significant differences between treatments and PBS control are shown with post-hoc Pairwise Mann–Whitney p-values (* p < 0.05, ** p < 0.01, *** p < 0.001).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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