FIGURE

Fig. 5

ID

ZDB-FIG-250311-157

Publication

Buchert et al., 2025 - Bi-allelic KICS2 mutations impair KICSTOR complex-mediated mTORC1 regulation, causing intellectual disability and epilepsy

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Fig. 5

Phosphoproteome data reveal differentially phosphorylated proteins linked to cilia and the centrosome (A) Number of differentially phosphorylated proteins compared to wild-type cells per sample and overlap between samples. (B) Percentage of proteins associated with cellular processes (mTOR, cilia, centrosome, transcription, translation, apoptosis, and proliferation) that are differentially phosphorylated when compared to wild-type cells. (C) Pathway analysis using IPA indicates changes in several pathways associated with mTOR activity (red), transcription (blue), translation (violet), and proliferation (green). Only the top 20 signaling pathways are shown.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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