FIGURE

Figure 7

ID

ZDB-FIG-250226-30

Publication

Zheng et al., 2025 - Exploring the Efficacy and Target Genes of Atractylodes Macrocephala Koidz Against Alzheimer's Disease Based on Multi-Omics, Computational Chemistry, and Experimental Verification

Other Figures

All Figure Page

Back to All Figure Page

Figure 7

MD simulations of six AMK ingredients with EGFR for 100 ns. (A) Simulation trajectories of six AMK ingredients with EGFR in the aqueous solution system for 100 ns. (B) RMSD plot of AMK ingredients with EGFR for 100 ns. (C) RMSF plot of AMK ingredients with EGFR for 100 ns. (D) High-flexibility amino acids (potentially reactive residues). (E) The number of AMK hydrogen bonds with EGFR for 100 ns. (F,G) Binding-free energies of AMK ingredients with EGFR for 100 ns. ΔGGAS = ΔVDWAALS + ΔEEL; ΔGSOLV = ΔEGB + ΔESURF; ΔTOTAL = ΔGGAS +ΔGSOLV. EGFR—Epidermal Growth Factor Receptor. ΔEEL—Electrostatic Interaction Energy ΔESURF—Nonpolar Solvation Energy, ΔEGB—Polar Solvation Energy.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Curr. Iss. Mol. Biol.