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Fig. 1
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- ZDB-FIG-250207-17
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- Chen et al., 2024 - An mRNA vaccine induces antimycobacterial immunity by activating DNA damage repair and autophagy
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Fig. 1
Construction and characterization of L3T mRNA vaccine (A) Scheme of the LPP-L3 mRNA design. (B) L3 protein expression in vitro (HEK293T cells) and in vivo (zebrafish larvae) at 24 hpost-transfection or post-injection of mRNA. (C and D) Neutrophil and macrophage recruitment at 4 and 24 h post-injection of 3 ng L3T mRNA (n ≥ 30). Blank: larvae without injection. PBS, LPP: larvae injected with PBS or LPP-GFP. Statistical analysis was performed using one-way ANOVA. ∗p < 0.05; ∗∗∗p < 0.001; ∗∗∗∗p < 0.0001. (E) L3T mRNA safety profile in larvae (n = 20). Blank: larvae without injection. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
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