FIGURE

Fig. 4

ID

ZDB-FIG-250128-40

Publication

Liu et al., 2024 - Resveratrol alleviates heart failure by activating foxo3a to counteract oxidative stress and apoptosis

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Fig. 4

Resveratrol mitigation of mitochondrial membrane potential disorder and oxidation experiment. (A) The remission of heart failure in zebrafish was observed by the heat map distribution of calcium signal activation time. The cardiac calcium signals of CaD90 (B), CaD30/80 (C), and CaD dispersion (D) in the RES exposure group were significantly decreased compared with those in the VPH group. (E) In the AC16 cell mitochondrial assay, it can be observed that the mitochondrial damage of AC16 cells was alleviated under the co-exposed of VPH and RES. (F) Reactive oxygen species assay, where a reduction in the degree of oxidative damage in zebrafish is observed when VPH and RES co-exposed. (G) AC16 cell JC-1 aggregate area. (H) AC16 cell JC-1 monomer area. (I) Reactive oxygen species assay with fluorescence intensity statistics. (Compared with the VPH group: *: P < 0.05, **: P < 0.05, ***: P < 0.001, ****: P < 0.0001, NS: not statistically different).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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