FIGURE

Fig. 7

ID

ZDB-FIG-250116-31

Publication

Lin et al., 2024 - Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis

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Fig. 7

Integrated mult-omics Analysis in HEPM cells. (A)The multi-group volcano plot showing the results of differential expression analysis in transcriptomics, proteomics, and metabolomics in HEPM Cells Exposed to 2 % CSE. In transcriptomics/proteomics, y-axis = log2FC. In metabolomics, y-axis = Variable Importance in Projection (VIP). Neg, the negative ion mode; pos, the positive ion mode. KEGG enrichment analysis of upregulated DEGs (B) and downregulated DEGs (C). (D) Overlap between molecules in the MAPK signaling pathway and differential expressed proteins (DEPs) as well as metabolic (DEMs). (E) The correlation network with strongly correlated moleculars. Green line, the positive correlation; purple line, the negative correlation. (F) The pathview of the MAPK signaling pathway with marked strongly correlated moleculars.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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