FIGURE

Fig. 1

ID

ZDB-FIG-250116-25

Publication

Lin et al., 2024 - Elucidating tobacco smoke-induced craniofacial deformities: Biomarker and MAPK signaling dysregulation unraveled by cross-species multi-omics analysis

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Fig. 1

Cigarette Smoke Extract Exposure Inhibits Craniofacial Development in Zebrafish Larvae. (A) Ventral views of Alcian-stained larval craniofacial cartilage exposed to cigarette smoke extract (CSE) for 7 dpf. Bar charts present quantitative data for various metrics: (B) ceratohyal (CH) Length; (C) palatoquadrate (PQ) Length; (D) CH-PQ Angle; (E) CH-CH Angle; (F) Meckel’s-Meckel’s Angle; (G) PQ-Meckel’s Angle in response to CSE exposure. Data represent the average of 3 independent experiments (10 larvae/replicate). * p < 0.05, ** p < 0.01, *** p < 0.001. (H) Cartilage sections of zebrafish larvae exposed to CSE were also examined by Hematoxylin and Eosin (HE) staining. Scale bars represent 50 μm (lower) and 100 μm (upper).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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