FIGURE

Figure 2

ID

ZDB-FIG-250109-279

Publication

Wang et al., 2024 - Insulin like growth factor 2 mRNA binding protein 2 regulates vascular development in cerebral arteriovenous malformations

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Figure 2

IGF2BP2 regulates vascular development-related pathways in endothelial cells. (A) Rank plot depicting differentially expressed genes between IGF2BP2 knockdown and control endothelial cells. (B) Venn diagram showing the intersection between downregulated genes in IGF2BP2 knockdown endothelial cells and genes downregulated at the level of m⁶A modification in METTL3-deficient or WTAP-deficient endothelial cells. (C) Network diagram displaying the results of enrichment analysis of target genes. (D) Sankey diagram showing the genes enriched in the vascular development-related pathways. (E) Bubble diagram displaying the expression levels between control and METTL3-deficient or WTAP-deficient endothelial cells. (F) Correlation analysis of IGF2BP2 expression with LGALS8 expression in cerebral AVMs. (G) Correlation analysis of IGF2BP2 expression with RNF213 expression in cerebral AVMs.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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