FIGURE

Fig. 3

ID

ZDB-FIG-241205-3

Publication

Bowley et al., 2024 - Zebrafish model for functional screening of flow-responsive genes controlling endothelial cell proliferation

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Fig. 3

Knock-down of candidate genes does not affect morphology or blood flow in the ISVs. Zebrafish embryos were injected with a gene-specific or non-targeting control MO. (A) Morphology of Tg(fli1a:LifeAct-mClover) embryos was observed during development and is shown here at 54 hpf. Lateral view, anterior to the left, dorsal up. Scale bar: 100 μm. (B) Blood flow was quantified in the ISVs of Tg(gata1a:dsRed) morphants at 72 hpf. n = 5 embryos per group.Mean values were compared using a Kruskal–Wallis test, none of the morphants had significantly different blood flow to the control.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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