FIGURE

Figure 4.

ID

ZDB-FIG-241031-12

Publication

Hosaka et al., 2024 - The zebrafish cerebellar neural circuits are involved in orienting behavior

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Figure 4.

reln mutants show defective orienting behavior. Orienting behavior of adult reln mutant homozygous fish (reln^Δ7/Δ7) and control heterozygous fish (reln^Δ7/+). A–C, Orienting behavior in two large tanks. The same genotype of fish was placed in both tanks. D, E, Orienting behavior toward wild-type control fish. A combination of large and small tanks was used. The test fish was placed in the large tank, while a wild-type fish was placed in the small tank. Percentages of the time spent in the ROI (B, D) and percentages of the time that fish showed the orienting angle (C, E) are indicated. reln^Δ7/Δ7 spent less time in the ROI and exhibited the orienting behavior for a shorter duration than controls in both the two large tank (n = 20 each in B, C) and large/small tank (n = 10 each in D, E) assays. Representative structures of time lag cross-correlation for reln^Δ7/+ and reln^Δ7/Δ7 fish (F). Black bars indicate latency from time 0 to peak. Quantification of latency to peak correlation in reln^Δ7/Δ7 and reln^Δ7/+fish (G). See Extended Data Figure 4-1 for more details.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

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Acknowledgments

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