FIGURE

Figure 5

ID

ZDB-FIG-241023-90

Publication

Feng et al., 2024 - siRNAs Targeting Non-Human Species-Specific lncRNAs Trigger Cell Death in Human Colorectal Cancer Cells

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Figure 5

siRNAs targeting zebrafish-specific lncRNA BX323557.1 do not cause death in normal human or mouse cancer cells (A) Schematic of genomic alignments of lncRNA BX323557.1 with human and mouse genome through UCSC Genome Browser. (B) Representative microscopic pictures of FHC and NCM460 cells treated with the specified siRNAs and (C) Percentages of the area covered by living cells. Scale bar, 100μm. (D -K) Total cell death was detected by flow cytometry in HCT116, DLD1, NCM460, and CT26 cells treated as indicated. All the data are presented in the format of mean ± SD from three independent experiments. ****p < 0.0001, ns, no significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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