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Fig. 1

ID

ZDB-FIG-240912-14

Publication

Liu et al., 2024 - Acute indomethacin exposure impairs cardiac development by affecting cardiac muscle contraction and inducing myocardial apoptosis in zebrafish (Danio rerio)

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Fig. 1

The developmental toxicity of indomethacin exposure in zebrafish embryos. (A) Determination of the median lethal concentration of indomethacin in zebrafish embryos after 96 h of exposure (n = 100 for each group). (B) The mortality rates of zebrafish embryos treated with indomethacin at different concentrations for 24?96 h (n = 100 for each group). (C) The hatching rate of zebrafish embryos exposed to indomethacin for 72 h (n = 100 for each group). (D) Determination of the body length of zebrafish embryos treated with different concentrations of indomethacin after 96 h of indomethacin exposure (n = 36 for each group). (E, F) Representative images and quantification of moving track graphs (E) and swimming distances (F) of zebrafish embryos treated with indomethacin at different concentrations for 96 h (n = 12 for each group). All values are presented as the mean � SEM. **P < 0.01, ***P < 0.001.

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