FIGURE

Fig. 3

ID

ZDB-FIG-240815-23

Publication

Brown et al., 2024 - Satellite glial cell manipulation prior to axotomy enhances developing dorsal root ganglion central branch regrowth into the spinal cord

Other Figures

All Figure Page

Back to All Figure Page

Fig. 3

Satellite glial cell ablation with central branch ablation improves central branch regrowth rate. (a) Diagram of dorsal root ganglion (DRG) central branch ablation (CBA) and satellite glia ablation (SGC-Abl) with CBA laser injury paradigms. (b) Percent of DRGs with successful and unsuccessful central branch regrowth into the dorsal spinal cord following CBA (n = 5/28 DRGs from 18 fish) with or without SGC-Abl (n = 9/17 DRGs from 14 fish; Pearson's ?² test, p = .033). (c) In vivo, time-lapse imaging of a Tg(ngn1:gfp;sox10:nls-eos) DRG at 3 dpf before (pre-injury) and after SGC-Abl CBA (?0 h postfertilization, hpf) with fluorescently labeled sensory neuron (asterisk; new dorsal neurite indicated by arrow) and SGC nuclei (white arrowheads). Spinal cord boundary indicated by dashed line. Single Z-plane inset indicated by square outline. Scale bars: 10 ?m. *p < .05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Glia