FIGURE

Fig. 4

ID

ZDB-FIG-240701-4

Publication

Flentke et al., 2024 - Alcohol exposure suppresses ribosome biogenesis and causes nucleolar stress in cranial neural crest cells

Other Figures

All Figure Page

Back to All Figure Page

Fig. 4

Alcohol causes apoptosis in the O9-1 cells and primary chick CNCs. Cells were exposed to alcohol at the EC50 (80mM for O9-1 cells, 52mM for primary CNCs) for 2hr and assessed at times thereafter. (A) Alcohol reduced the percentage of EdU+ proliferating cells in O9-1 cells 12hr after exposure. (B) Alcohol increased the percentage of Annexin-V+ (red) cells in O9-1 cells 6hr after exposure. (C) Alcohol increased the percentage of TUNEL+ (red) O9-1 cells 18hr after exposure. (D) Alcohol increased the percentage of TUNEL+ (green) primary chick CNCs at 18hr after exposure. Values are the mean ± SEM of 5–8 independent experiments. Data were analyzed using two-tailed Student’s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS One