FIGURE

Fig. 3.

ID

ZDB-FIG-240606-61

Publication

Isiaku et al., 2024 - A nox2/cybb zebrafish mutant with defective myeloid cell reactive oxygen species production displays normal initial neutrophil recruitment to sterile tail injuries

Other Figures

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Fig. 3.

Reduced viability of embryos carrying the nox2 mutant allele. a) Survival curve of concurrent cohorts of WT and nox2−/− zebrafish embryos. b) Survival curve of concurrent cohorts of WT, nox2+/−, and nox2−/− zebrafish embryos. c) Twenty-four (24) h viability of nox2 WT, heterozygous, and homozygous zebrafish embryos. Panels a, b, and c were performed independently on different days and represent cohorts of genotype-identical embryos assayed in parallel. N-values in brackets (a, b) and within columns (c)—note that although N-values are similar, a and b are independent experiments; +/+, WT; +/−, heterozygous; −/−, homozygous. Log-rank (Mantel–Cox) tests (a, b), Fisher’s exact test (c), P < 0.0001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	cybb^gl43/gl43 (TU) cybb^gl43/+ (TU)
Observed In:	whole organism
Stage Range:	Prim-5 to Day 5

Phenotype Detail

Acknowledgments

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