FIGURE

Fig 5

ID

ZDB-FIG-240412-39

Publication

Bhattarai et al., 2024 - Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease

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Fig 5

Changes in FN1 and COL6A2 according to APOE genotype. a–c′ Double IFS for CD31 (green) and FN1 (red) with DAPI nuclear counterstain in APOEε3/3 (a, a′), APOEε3/4 (b, b′) and APOEε4/4 (c, c′). d FN1 and CD31 intensity comparisons in 2,044 blood vessels from 28 individuals. e Regression model for FN1 intensity with respect to blood vessel diameter in three APOE genotypes. f–h′ Double IFS for COL4 (green) and COL6A2 (red) with DAPI nuclear counterstain in APOEε3/3 (f, f′), APOEε3/4 (g, g′) and APOEε4/4 (h, h′). i COL4 and COL6A2 intensity comparisons in 1,816 blood vessels from 28 individuals. j Regression model for COL6A2 intensity with respect to blood vessel diameter in three APOE genotypes. Scale bars equal 100 μm

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Acta Neuropathol.