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Fig 5

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Publication: Bhattarai et al., 2024 - Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease
All Figures: Figures for Bhattarai et al., 2024

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Fig 5

Changes in FN1 and COL6A2 according to APOE genotype. a–c′ Double IFS for CD31 (green) and FN1 (red) with DAPI nuclear counterstain in APOEε3/3 (a, a′), APOEε3/4 (b, b′) and APOEε4/4 (c, c′). d FN1 and CD31 intensity comparisons in 2,044 blood vessels from 28 individuals. e Regression model for FN1 intensity with respect to blood vessel diameter in three APOE genotypes. f–h′ Double IFS for COL4 (green) and COL6A2 (red) with DAPI nuclear counterstain in APOEε3/3 (f, f′), APOEε3/4 (g, g′) and APOEε4/4 (h, h′). i COL4 and COL6A2 intensity comparisons in 1,816 blood vessels from 28 individuals. j Regression model for COL6A2 intensity with respect to blood vessel diameter in three APOE genotypes. Scale bars equal 100 μm

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