FIGURE

Figure 2

ID

ZDB-FIG-240226-119

Publication

Adel et al., 2024 - Decreased Brain Serotonin in rbfox1 Mutant Zebrafish and Partial Reversion of Behavioural Alterations by the SSRI Fluoxetine

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Figure 2

Behaviour of wildtype and rbfox1^{sa15940/sa15940} zebrafish after exposure to fluoxetine in the Open Field. Adult zebrafish were tested in the Open Field paradigm after exposure to water (control group) or to different concentrations of fluoxetine for one hour prior to testing. (A) Total swimming distance; (B) mean speed; (C) time spent freezing; (D) time spent in the inner 50% of the arena; WT = wildtype, rbfox1^{sa15940/sa15940} = homozygous mutants, control = 0 µg/L fluoxetine, N = 10 per group; permutation two-way ANOVA with interaction followed by post hoc permutational analysis using Benjamini and Hochberg correction; mean ± SD; * p_adj < 0.05, *** p_adj < 0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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