FIGURE

Figure 3

ID

ZDB-FIG-240215-99

Publication

Raas et al., 2024 - Generation and characterization of a zebrafish gain-of-function ACOX1 Mitchell disease model

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Figure 3

Characterization of zebrafish mutant experiments by overexpression of human ACOX1 N237S. (A) Schematic diagram of experiments. (B) Zebrafish show abnormal motor (swimming) behavior, which is rescued by D-NAC. ***p < 0.001. (C) qRT-PCR characterization of transcripts. Expression of mutant form does not impact myelin transcripts or general inflammatory markers but does activate the ISR (atf4).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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