Fig. 3
- ID
- ZDB-FIG-240126-35
- Publication
- Shihana et al., 2023 - Investigating the role of lipid genes in liver disease using fatty liver models of alcohol and high fat in zebrafish (Danio rerio)
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Ethanol or HFD exposure altered expression of genes in lipid biology pathways in zebrafish larvae. Lipid biology genes expression in pnpla3, faf2 and tm6sf2 crispants on 5 dpf following 48 h of exposure to (A) 2% EtOH or (B) HFD. qPCR analysis was used to detect the expression of lipid-related genes relative to 18S. The average fold change was normalised to the expression in scramble control. Y-axis represents the foldchange over scramble control (marked in dotted line). Each point represents data pooled from10 to 15 zebrafish larvae per treatment. Error bars indicate interquartile range of the median. The ordinary one-way ANOVA with selected pair test was used to calculate the statistical significance. |