FIGURE

Fig. 5.

ID

ZDB-FIG-240123-5

Publication

Juan et al., 2024 - Control of cardiac contractions using Cre-lox and degron strategies in zebrafish

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Fig. 5.

The cardiac transcriptomes of Tnnt2a degrons and tnnt2a mutants display high similarity at the single cell level. (A) Schematic and description of the sample preparation for single-cell RNA-sequencing; 100 hearts from 72 hpf WT, tnnt2a^{mn0031Gt/mn0031Gt} (Mutant), and tnnt2a^{mn0031Gt/bns513}; myl7:zGRAD-P2A-TagBFP^+/− (Degron) larvae were dissected, dissociated and the single cell suspension sequenced. (B) Uniform manifold approximation and projection (UMAP) representation of the data; stacked columns represent the numbers of WT (green), mutant (orange), and degron (violet) cells for each annotated population; UMAP is displayed merged (Left) or split by genotype (Right).

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Proc. Natl. Acad. Sci. USA