Fig. 5
- ID
- ZDB-FIG-240112-77
- Publication
- Travisano et al., 2023 - Single-nuclei multiomic analyses identify human cardiac lymphatic endothelial cells associated with coronary arteries in the epicardium
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snMultiomic analyses of 11PCW (A) UMAP of snRNA-seq data for all cells of the 11PCW hearts showing several endothelial clusters. (B) UMAP of chromatin accessibility labeled as snATAC-seq at 11PCW. (C) UMAP of gene expression and chromatin accessibility computed using the WNN and labeled as snMultiome. (D) Violin plots showing distribution of PROX1, FLT4, LYVE1, MRC1, and PDPN from the 11PCW dataset. (E) Motif enrichment analysis showing positive enrichments of the top 6 position weight matrix (PWM) from the LEC cluster at 11PCW. (F) Volcano plot showing positive enrichments of the motifs from the LEC cluster. (G) UMAP generated by ECs subclusters of the 11PCW dataset. (H) Dot plot depicting both the expression level and the percentage of cells expressing selected genes from the EC clusters and lymphatic markers. |