FIGURE

Fig. 6

ID

ZDB-FIG-231228-98

Publication

Park et al., 2023 - Narirutin ameliorates alcohol-induced liver injury by targeting MAPK14 in zebrafish larvae

Other Figures

All Figure Page

Back to All Figure Page

Fig. 6

NRT attenuates endoplasmic reticulum (ER) stress and mitochondria function in zebrafish larvae with alcoholic injury. (A) mRNA expression of genes associated with ER stress upstream regulator (atf4, atf6, ire1), pro-survival (xbp1-unsplicing, xbp1-splicing), molecular chaperon (bip, dnajc3, grp94) and cell death (ddit3, edem1, gadd45a). (B) Changes of genes associated with mitochondrial injury (bim, bida, baxb) in EtOH-treated zebrafish larvae by NRT (n = 15/group, three independent experiments). (C) Protein expression levels of Ddit3, Bip and Gapdh. Quantification of band intensity of Ddit3 and Bip was calculated by Gadph as a housekeeping protein (n = 5 biologically independent experiments). The data are presented as the mean ± SD; a,b,c,d mean values with different superscript letters are significantly different among the groups (p < 0.05).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biomed. Pharmacother.