FIGURE

Fig. 3

ID

ZDB-FIG-231215-145

Publication

Dai et al., 2022 - Csf1rb regulates definitive hematopoiesis in zebrafish

Other Figures

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Fig. 3

Csf1rb deficiency impairs the proliferation capacity of HSPCs. (A) Immunostaining of cmyb-GFP (green) and BrdU (red) in the CHT at 3 dpf in siblings and csf1rb mutants after BrdU labeling for 1 h. Yellow arrows show BrdU+ HSPCs, white arrows indicate GFP single-positive HSPCs. Scale bars: 20 μm. (B) Quantification of cmyb-GFP+ HSPCs in the CHT at 3 dpf in siblings (n=16) and csf1rb mutants (n=19). (C) Quantification of the proliferation ratio of cmyb-GFP+ HSPCs in the CHT at 3 dpf in siblings (n=16) and csf1rb mutants (n=19). Data are presented as mean±s.e.m. **P<0.01.

Expression Data

Gene:	GFP
Fish:	csf1rb^hkz50/hkz50; zf169Tg/zf169Tg
Anatomical Term:	caudal hematopoietic tissue hematopoietic multipotent progenitor cell
Stage:	Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	csf1rb^hkz50/hkz50; zf169Tg/zf169Tg
Observed In:	caudal hematopoietic tissue hematopoietic multipotent progenitor cell hematopoietic multipotent progenitor cell cell division
Stage:	Protruding-mouth

Phenotype Detail

Acknowledgments

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