FIGURE

FIGURE 7

ID

ZDB-FIG-231130-58

Publication

Belmonte-Mateos et al., 2023 - Hindbrain rhombomere centers harbor a heterogenous population of dividing progenitors which rely on Notch signaling

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FIGURE 7

notch3 mutation accounts for the loss of Notch activity in the center of the rhombomeres and results in neuronal differentiation. (A–J) Control and notch3^fh322/fh322 embryos in the Tg[tp1:d2GFP] background were in situ hybridized with fabp7a (B, G), ascl1b(C,H), neuroD4(D,I), or hey1(E,J) at 48 hpf. (K–N) Control and hey1^ha11/ha11 embryos were in situ hybridized with fabp7a(K,M) and ascl1b(L,N) at 48 hpf. Dorsal MIP with anterior to the top. White arrowheads indicate the rhombomere boundaries. Numbers at the bottom indicate the individuals with the displayed phenotype over the total of analyzed specimens. As control embryos, either wild-type or heterozygous embryos were used. Scale bar, 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol