FIGURE

FIGURE 4

ID

ZDB-FIG-231114-7

Publication

Tarbashevich et al., 2023 - The mitochondrial protein Sod2 is important for the migration, maintenance, and fitness of germ cells

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FIGURE 4

Defects in protrusion formation and germ cell polarity in sod2 KO and neomycin-treated embryos. Analysis of (A, D) the number of blebs in PGCs per minute and (B, E) the proportion of blebs at the cell back. In graphs A and B, MZsod2^STOP31 embryos were injected with control RNA or with RNA directing Sod2 expression to the germ cells (see Methods); the same cells were analyzed in panels A and (B). In graphs D and E, wild-type embryos were treated with DMSO or with neomycin; the same cells were analyzed in panels D and (E). (C, F) Snapshots from the representative time-lapse movies (movies S1 and S2) analyzed in (A,B,D, E). Yellow asterisks point at blebs at the rear of cells. n - the number of PGCs analyzed. One PGC per embryo was imaged and analyzed. **p < 0.01, *p < 0.05, were calculated by Student’s t-test.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol