FIGURE

Fig. 3

ID

ZDB-FIG-231113-17

Publication

Zou et al., 2023 - Determining zebrafish dorsal organizer size by a negative feedback loop between canonical/non-canonical Wnts and Tlr4/NFκB

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Fig. 3

Rel negatively regulates Wnt/β-catenin signaling.

Wnt/β-catenin signaling is enhanced by rel knockdown (a, b) and decreased by rel overexpression (c, d) at the dome stage. WISH (a, c) and qPCR analysis (b, d) of axin2 and sp5l in dome-stage WT embryos injected with ctrl MO, rel MO, control (mKO2) or rel mRNA. In a and c, animal views are shown. Scale bar = 200 μm. In b and d, normalized values are shown as mean ± SEM. n = 3 biologically independent samples. P-values from unpaired two-tailed t-tests are indicated. Source data are provided as a Source Data file.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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