FIGURE

Figure 7

ID

ZDB-FIG-231019-20

Publication

Wu et al., 2023 - The Neuroprotective Effect of Isotetrandrine on Parkinson's Disease via Anti-Inflammation and Antiapoptosis In Vitro and In Vivo

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Figure 7

Effect of LY294002, LY3214996, and SnPP on ITD antiapoptotic effect in 6-OHDA-treated zebrafish in mRNA level. Zebrafish larvae were pretreated with 20 μM LY294002, 20 μM LY3214996, or 40 μM SnPP, and 200 μM ITD from 9 hpf to 5 dpf and then challenged with 250 μM 6-OHDA from 2 to 5 dpf and harvested at 5 dpf for qPCR. Quantitative PCR results of (a) th1, (b) bcl-2, (c) bax, and (d) ho-1 at (a) 5 dpf and (b) 6 dpf. Data are presented as mean ± SEM (n = 3). Each sample contained pooled material from twenty fish. ^∗significantly different from the control group; ^#significantly different from the 6-OHDA group; &, significantly different from the 6-OHDA plus ITD group; p < 0.05.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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