FIGURE

Fig. 5.

ID

ZDB-FIG-231018-31

Publication

Ali et al., 2023 - Loss of a cilia-associated gene, pkd1l1, causes biliary defects in zebrafish: Implications for Biliary Atresia Splenic Malformation

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Fig. 5.

pkd1l1 mutant zebrafish have abnormal liver biochemistry. Whole livers were isolated from 6-week-old zebrafish and homogenized for protein assays. (A) Total liver protein concentration showed no significant differences between wild-type and pkd1l1 mutant livers (n=16). (B,C) ALT (B) and GGT (C) enzyme assays showed a significant increase in enzyme activity in pkd1l1 mutant livers compared to that in wild-type livers (n=15). Graphs show the mean±s.e.m. ns, not significant; ***P<0.001; ****P<0.0001 (unpaired two-tailed Student's t-test).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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