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Figure 4

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ZDB-FIG-231002-345

Publication

Farre et al., 2023 - Plasticity of cone photoreceptors in adult zebrafish revealed by thyroid hormone exposure

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Figure 4

Plasticity of cone transcripts in response to 12-h T4 treatment. (A–F) Projections of representative whole, imaged retinas from fish treated with NaOH (control, A–C) or T4 (treated, D–F) followed by HCR in situ. Insets show indicated regions enlarged by 1400%. (A,D) All imaging channels merged. (B,E) lws2 (C,F) lws1. Note expanded lws1 domain and colocalization of lws1 and lws2 mRNA in T4-treated retina. (G) qPCR of whole adult eyes. (lws1) n = 6 (control), 4 (treated); p = 0.0006 (t-test). (lws2) n = 6 (control), 4 (treated); p = 0.1424 (t-test). (gngt2b) n = 6 (control), 4 (treated); p = 0.7863 (t-test). (rh2-1) n = 6 (control), n = 5 (treated); p = 0.1860 (t-test). (rh2-2) n = 6 (control), n = 5 (treated); p = 0.3820 (t-test). D dorsal, T temporal.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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