FIGURE

Figure 1

ID

ZDB-FIG-230731-98

Publication

Cannone et al., 2023 - Human Mutated MYOT and CRYAB Genes Cause a Myopathic Phenotype in Zebrafish

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Figure 1

Light microscopy of the muscle biopsy from control subject (A–C) and patient with p.Gly154Ser CRYAB mutation (D–F). No morphological abnormalities with haematoxylin and eosin (A), modified Gomori trichrome (B) and NADH (C) staining in control subject. Haematoxylin and eosin (D) staining shows fiber size variation in MFM patient. Muscle fibers with amorphous material that stains eosinophilic on haematoxylin and eosin (D) and dark blue on modified Gomori trichrome (E) are also observed (arrows); these fibers have irregular focal areas of decreased or increased NADH staining (F) (arrows). Images were obtained with obj ×20. Scale bar: 50 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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