FIGURE

Figure 4

ID

ZDB-FIG-230709-12

Publication

Hoareau et al., 2023 - Characterization of the Zebrafish Elastin a (elna^sa12235) Mutant: A New Model of Elastinopathy Leading to Heart Valve Defects

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Figure 4

elna mutants are subject to cardiomegaly with age. Zebrafish hearts were collected from apparently healthy fish at 12 (A) or 22 (B) mpf (n = 4 fish per genotype and age). Representative images are shown for each genotype. The area of the ventricle and the bulbus arteriosus (including dysplastic tissue) was measured in each heart and reported, normalized with the size of the fish. Data were analyzed by Kruskal–Wallis with Dunn’s multiple comparison test; * p < 0.05. Scale bar = 0.5 mm. mpf = months post fertilization; WT = wild type (elna^+/+); HET = heterozygous (elna^sa12235/+); MUT = mutant (elna^{sa12235/sa12235}).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	elna^{sa12235/sa12235}
Observed In:	cardiac ventricle
Stage:	Adult

Phenotype Detail

Acknowledgments

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