FIGURE

FIGURE 1

ID

ZDB-FIG-230629-88

Publication

Lee et al., 2023 - IFT46 gene promoter-driven ciliopathy disease model in zebrafish

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 1

Transient expression of IFT46:GAL4-VP16 in ciliated cells. (A) Schematic representation of the 5′ upstream regulatory region of the IFT46 gene that contains putative two RFX2 transcription factor-binding site sequences (red arrowheads). (B) Schematic view of the Tol2-based construct containing GAL4-VP16 under the control of the 2.4 kb IFT46 promoter. (C) Two-color in situ hybridization of the GAL4-VP16 chimeric transcription factor (red) with odf3b (blue) at 24 hpf. GAL4-VP16 transcripts are expressed in multi-ciliated cells (box region) in the distal segment of the pronephric duct (red arrows). Scale bar: 200 μm (C).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Cell Dev Biol